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Myeloid Sarcoma in the Central Nervous System: Case Report and Review of the Literature

Walter Struhal
Stefan Oberndorfer
Heinz Lahrmann
Elisabeth Lindeck-Pozza
Barbara Hess
Vera Nussgruber
Rainer Pöhnl
Thomas Dobner
Wolfgang Grisold

Sažetak

Myeloid sarcomas are rare manifestations of mainly myeloblastic leukemia. Their occurrence in the central nervous system is exceptional and current literature is limited to case studies. A case is added herewith and a review was performed to investigate clinical characteristics and treatment options of central nervous system myeloid sarcoma. A 61-year-old female with acute myeloblastic leukemia (FAB M5) and progressive left sided hemiparesis showed a right parieto-occipital epidural lesion mimicking meningioma. Partial resection was performed to reveal a myeloid sarcoma. Reviewing the literature we identified 44 cases with sufficient description of the diagnosis, treatment and follow up to one year. In these patients different treatment regimens were applied. However, when systemic chemotherapy or irradiation was included in the treatment regimen, patients showed the best 1-year survival proportion.

Ključne riječi

Leukemia myeloid - complications; Meningeal neoplasms - diagnosis; Central nervous system - pathology

Hrčak ID:

25815

URI

https://hrcak.srce.hr/25815

Datum izdavanja:

3.3.2008.

Podaci na drugim jezicima: hrvatski

Posjeta: 4.013 *