Pregledni rad
https://doi.org/10.20471/acc.2022.61.s1.09
Prothrombin Complex Concentrate in Emergency Department
Višnja Nesek Adam
orcid.org/0000-0002-6521-4136
; Emergency Department, Clinical Hospital Sveti Duh, Zagreb, Croatia; Faculty of Dental Medicine and Health, Osijek, Croatia; Libertas Interantional University, Zagreb, Croatia
Ingrid Bošan-Kilibarda
; Croatian Institute for Emergency Medicine, Croatia
Sažetak
Coagulation abnormalities are common in bleeding or critically ill patient and
hemostatic management remains a major challenge for the emergency physician. Management of
bleeding patients consists of bleeding control, restoration of blood volume, and correction of any associated
coagulopathy. Traditionally, the fresh frozen plasma (FFP) is used for correction of coagulopathy
to manage and prevent bleeding, but today Prothrombin complex concentrates (PCCs) offer
an attractive alternative because they offers a number of advantages over FFP, including lower infusion
volume, rapid IN R normalization, faster availability, lack of blood group specificity, and better
safety profile. The aim of the present review is to provide an short overview about using PCC, their
indication, efficacy and safety in different bleeding setting’s.
Ključne riječi
bleeding; emergency department; prothrombin complex concentrates
Hrčak ID:
281189
URI
Datum izdavanja:
1.6.2022.
Posjeta: 1.691 *