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Clear cell sarcoma – a case report

Vesna Ramljak ; Department of Clinical Cytology, University Hospital for Tumors, Zagreb, Croatia
Irena Ranogajec ; Department of Clinical Cytology, University Hospital for Tumors, Zagreb, Croatia
Irena Novosel ; Department of Pathology, Dr Ivo Pedišić General Hospital, Sisak, Croatia
Vištpr Šeparović ; Department of Pathology, University Hospital for Tumors, Zagreb, Croatia
Danko Velimir Vrdoljak ; Department of Surgery, University Hospital for Tumors, Zagreb, Croatia


Puni tekst: engleski pdf 148 Kb

str. 53-58

preuzimanja: 80

citiraj


Sažetak

The report covers the first case of clear cell sarcoma (malignant melanoma of soft tissue) recorded in the Croatian medical literature.
It is a rare soft tissue tumor, constituting less than 1% of all soft tissue neoplasms, first reported by Enzinger in 1965. The tumor presents most often in adolescents and young adults, with its peak incidence in the third and fourth decade and slight female predominance.
The tumor produces melanin, but it differs from melanoma in several important respects. The proper name for this neoplasm should be clear cell sarcoma of tendons and aponeuroses in order to prevent confusion with clear cell sarcoma of the kidney and other clear and spindle cell neoplasms.
A 23-year-old female patient presented to our hospital with a 10 cm large, painless, lower right leg mass, and few palpable lymph nodes in the ipsilateral inguinum. Clinical examination (NMR, ultrasound ) showed an expansive tumor mass and few suspicious inguinal lymph nodes. Surgical treatment was indicated because of cytologically suspicious diagnosis of clear cell sarcoma or malignant melanoma .
Histopathological and immunohistochemical analysis confirmed the origin of tumor cells and showed melanoma/ melanocytic differentiation including clear cell sarcoma (malignant melanoma of soft tissue).
This case report provides evidence that the preoperative definitive diagnosis of primary CCSSP can be rendered if immunocytochemistry is used in addition to cytomorphology in a suitable clinical setting.

Ključne riječi

clear cell sarcoma; FNA cytology

Hrčak ID:

281743

URI

https://hrcak.srce.hr/281743

Datum izdavanja:

20.12.2004.

Podaci na drugim jezicima: hrvatski

Posjeta: 328 *