Review article
https://doi.org/10.15255/KUI.2022.003
Solid Phase Microextraction – An Innovative Approach to Bioanalytical Research
Ana Mornar
orcid.org/0000-0002-3944-697X
; Department of Pharmaceutical Analysis, University of Zagreb, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia
Iva Marinac-Anđić
; Department of Pharmaceutical Analysis, University of Zagreb, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia
Daniela Amidžić Klarić
orcid.org/0000-0002-1695-6950
; Department of Pharmaceutical Analysis, University of Zagreb, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia
Jelena Kovačić
; Department of Pharmaceutical Analysis, University of Zagreb, Faculty of Pharmacy and Biochemistry, A. Kovačića 1, 10 000 Zagreb, Croatia
Abstract
In last three decades, the solid-phase microextraction technology has brought significant progress in bioanalytical research due to the versatility of this fast and solvent-free approach to biological sample preparation. It has been widely used in combination with various analytical instrumentation, even if most of the work has been done by coupling the extraction technique with liquid or gas chromatography. This review focuses on the new developments and advances in solid-phase microextraction-based techniques. Furthermore, some interesting, new innovations that fail to go beyond academic research are also reported.
Keywords
bioanalysis; sample preparation; solid-phase microextraction; therapeutic drug monitoring
Hrčak ID:
283655
URI
Publication date:
21.9.2022.
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