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https://doi.org/10.5599/jese.2718

NiMoO4 nanosheets modified carbon paste electrode for simultaneous determination of epinine and dobutamine

Falah H. Abdullah ; Department of Forensic Sciences, College of Health and Medical Technology, National University of Science and Technology, Dhi Qar, Iraq
Ibrahim Ayad Jihad ; Department of Chemistry and Biochemistry, Al-Zahraa College of Medicine, University of Basrah, Iraq
Talib Saddam Mohsin ; Department of Anesthesia Techniques, Kut University College, Wasit, Iraq
Mustafa Mudhafar ; aculty of Medical Applied Sciences, University of Kerbala, Karbala, Iraq and Al-Taff University College, Kerbala, Iraq
Raed Muslim Muhibes ; Department of Biochemistry, College of Medicine Misan University, Iraq *

* Dopisni autor.


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Sažetak

In this work, a carbon paste electrode was modified with ionic liquids and NiMoO4 nanosheets (NMs/IL/CPE) for voltammetric epinine detection. The NMs/IL/CPE showed good electro­catalytic activity for epinine oxidation compared to unmodified CPE. The limit of detection is 0.05 μM, and under ideal circumstances, the oxidation peak currents of epinine show a linear relationship with epinine concentration from 0.1 to 300.0 μM. Additionally, when dobutamine was present, the NMs/IL/CPE showed good activity toward epinine determi­na­tion. Its appropriateness for the simultaneous detection of these two medicines using dif­ferential pulse voltammetry is shown by the separation of the oxidation peak potentials of 200 mV. Lastly, epinine and dobutamine analysis in real specimens confirmed the proposed sensor's applicability with outstanding findings (recovery 96.0 to 103.5 %, and relative standard deviation <3.6 %).

Ključne riječi

Electrochemical sensor; deoxyepinephrine; catecholamine; cardiovascular disease; dobutamine

Hrčak ID:

333145

URI

https://hrcak.srce.hr/333145

Datum izdavanja:

1.5.2025.

Posjeta: 525 *