Sažetak sa skupa
Chondrosarcoma of the larynx – a case report with a brief literature review
Tomislav Sušac
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina; Sveučilište u Mostaru, Medicinski fakultet, 88000 Mostar, Bosna i Hercegovina
Josip Lesko
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina; Sveučilište u Mostaru, Medicinski fakultet, 88000 Mostar, Bosna i Hercegovina
Irena Pehar
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina
Miro Leventić
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina; Sveučilište u Mostaru, Medicinski fakultet, 88000 Mostar, Bosna i Hercegovina
Anamarija Mikulić
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina
Boris Jelavić
; SKB Mostar, Bijeli brijeg bb, 88000 Mostar, Bosna i Hercegovina; Sveučilište u Mostaru, Medicinski fakultet, 88000 Mostar, Bosna i Hercegovina
Sažetak
This case report presents a 65-year-old male with a primary complaint for hoarseness. There were no
difficulties in breathing or swallowing, and he had a neck lump. The endoscopic appearance revealed poor
mobility of the right vocal cord and swollen and prominent right lateral and posterior wall of the subglottic
area, covered with intact mucosa. Neck ultrasonography and MSCT showed no suspicious pathologic lymph
nodes but MSCT revealed pathologic growth (44 x 35 x 30 mm), containing calcifications, circularly infiltrated
into the cricoid cartilage and caudally into the trachea. Two direct laryngoscopies with biopsy were performed
but there was no histopathological evidence of malignancy. Finally, a tissue sample obtained by a third biopsy
revealed malignant cells. Control neck MSCT showed a size enlargement of the tumor (47 x 45 x 30 mm). A
total laryngectomy was done. Histopathologic diagnosis of grade 3 laryngeal chondrosarcoma was established.
The patient was discussed at the Oncology Tumor Board, and postoperative radiotherapy was indicated and
completed without complications. A brief literature review revealed 766 laryngeal chondrosarcoma cases
reported in English literature. Most of the patients were in the seventh decade of life. There were more males
than females (the ratio 3:1). The most common surgical approaches were local excision and total laryngectomy.
Radiotherapy and chemotherapy were rarely used in less than 1% of cases. The disease-specific 5-year survival
rate was 91.4% with no differences when comparing the rates for location, grade, and therapy. A submucosal
spread of chondrosarcoma often resulted in histopathological diagnoses which were false negative for
malignancy. Therefore, an alternative open approach and laryngeal tissue harvesting through the cricoid
cartilage fissure was recommended.
Ključne riječi
larynx; chondrosarcoma; biopsy; surgical treatment
Hrčak ID:
336437
URI
Datum izdavanja:
10.11.2025.
Posjeta: 119 *