Medicina Fluminensis, Vol. 62 No. 1, 2026.
Izvorni znanstveni članak
https://doi.org/10.21860/medflum2026_343564
The Role of Radiotherapy in the Treatment of Lymphoma: Clinical Experience of the Clinic for Tumors, University Hospital Centre Rijeka
Sanja Ropac
; Klinički bolnički centar Rijeka, Klinika za tumore, Rijeka, Hrvatska; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Ivana Mikolašević
; Klinički bolnički centar Rijeka, Klinika za tumore, Rijeka, Hrvatska; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Tihana Salopek
; Klinički bolnički centar Rijeka, Klinika za tumore, Rijeka, Hrvatska
Đeni Smilović Radojčić
; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska; Klinički bolnički centar Rijeka, Zavod za medicinsku fiziku i zaštitu od zračenja, Rijeka, Hrvatska
Damir Vučinić
orcid.org/0000-0002-5804-0799
; Klinički bolnički centar Rijeka, Klinika za tumore, Rijeka, Hrvatska; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
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* Dopisni autor.
Sažetak
Aim: This paper presents the one-year experience of our radiotherapy center in treating lymphoma. Patients and methods: We included patients diagnosed with HL or NHL who began radiotherapy treatment between August 2022 and September 2023. All patients had previously received chemotherapy. Data collected included age, sex, type and location of lymphoma, prescribed total dose of radiotherapy, radiation technique, and radiological response after the treatment completion. Results: Based on anatomical localization, most patients underwent supradiaphragmatic radiotherapy, primarily targeting the head and neck region, followed by the axillary region and mediastinum. Approximately one-third of patients presented with infra-diaphragmatic lymphoma, most often in the inguinal region. The most used radiation therapy technique was 3D conformal radiotherapy. Involved site radiotherapy (ISRT) was performed more frequently than involved field radiotherapy (IFRT). The median irradiation dose in the ISRT group was 32.4 Gy, compared to 33 Gy in the IFRT group. The median daily dose in both groups was 1.8 Gy. IMRT and 3D CRT techniques were equally represented in the IFRT group, while the 3D CRT technique was more prevalent in the ISRT group. Grade I side effects were noted in two patients in the IFRT group, with both cases reporting stomatitis. Two patients in the ISRT group experienced a grade I side effect in the form of skin erythema. Thirty patients (86 %) achieved a complete response, four patients (11 %) had a partial response, and one patient (3 %) showed no response to radiotherapy. Conclusions: Radiotherapy remains a crucial modality for lymphoma treatment. Reducing doses and radiation volumes enhances local tolerability while maintaining excellent response rates.
Ključne riječi
intensity-modulated radiotherapy; lymphoma; radiotherapy; treatment outcome
Hrčak ID:
343564
URI
Datum izdavanja:
1.3.2026.
Posjeta: 216 *