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Hrvatski veterinarski vjesnik, Vol. 34 No. 2, 2026.

Pregledni rad

Hereditary breeding diseases in large breed dogs: degenerative myelopathy and polyneuropathy

Sven Menčik ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska *
Mihovila Balen ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Anamaria Ekert Kabalin ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Mario Ostović orcid id orcid.org/0000-0002-0253-0000 ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Velimir Sušić ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Hrvoje Capak orcid id orcid.org/0000-0001-6128-7365 ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Lidija Medven Zagradišnik orcid id orcid.org/0000-0001-6182-6015 ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Maja Maurić Maljković ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Ivan Vlahek ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska

* Dopisni autor.

Puni tekst: hrvatski pdf 223 Kb

str. 56-64

preuzimanja: 0

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Sažetak

Hereditary diseases are becoming increasingly common in large breed dog breeding due to the reduced genetic variability within individual breeds. Over centuries, inbreeding, the presence of mutations, and the increased frequency of potentially harmful gene variants (alleles) have affected health and resistance traits, particularly in large dog breeds. Testing individuals with the most advanced molecular genetic methods is essential for understanding the genotype, the origin of the disease, and the most effective breeding strategies, including tailored treatment, especially in cases of neurodegenerative diseases in large breed dogs, such as degenerative myelopathy and polyneuropathy. The diversity of alleles in dog breeds highlights the need for further research, particularly into the role of individual dominant or recessive alleles. Comparative genetic studies aim to expand knowledge about the impact of existing mutations on genetic variability at specific loci of interest, all with the goal of preserving the breed and improving the health and welfare of dogs.

Ključne riječi

dog; hereditary diseases; degenerative myelopathy; polyneuropathy

Hrčak ID:

348106

URI

https://hrcak.srce.hr/348106

Datum izdavanja:

19.6.2026.

Podaci na drugim jezicima: hrvatski

Posjeta: 0 *