Izvorni znanstveni članak
https://doi.org/https://doi.org/10.5599/jese.3126
Bismuth molybdate nanostructure modified carbon paste electrode for voltammetric sensing of levodopa in the presence of acetaminophen
Abdul Amir H. Kadhum
Ahmed J. Allami
Hajir M. Ali
Huda Hadi Nameh
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* Dopisni autor.
Sažetak
In the present work, a voltammetric sensor for levodopa (L-DOPA) was fabricated based on Bi2MoO6 nanostructure-modified carbon paste electrodes (Bi2MoO6/CPE). Bi2MoO6 nanostructures were synthesized via the solvothermal procedure and characterized by X-ray diffraction pattern. The Bi₂MoO₆/CPE exhibited an enhanced current response for L-DOPA, which we attribute to the good electrocatalytic activity of the Bi2MoO6 nanostructures. Furthermore, the Bi2MoO6/CPE sensor was applied to determine L-DOPA in the presence of acetaminophen (ACT). The anodic peaks for L-DOPA and ACT were well-resolved in their mixture, enabling their simultaneous determination. The voltammetric measurements at pH 7.0 revealed distinct anodic peaks for the two analytes, located at approximately 350 mV (L-DOPA) and 530 mV (ACT). Using differential pulse voltammetry, a linear correlation was observed between the oxidation peak current and L-DOPA concentration over the range 0.02 to 590.0 μM. The limit of detection was determined to be 0.009 μM. The practical applicability of the Bi2MoO6/CPE sensor was successfully demonstrated through the assay of L-DOPA and ACT in real samples.
Ključne riječi
Parkinson's disease; Bi2MoO6 nanostructures, real sample analysis, chronoamperometry
Hrčak ID:
351133
URI
Datum izdavanja:
10.5.2026.
Posjeta: 0 *