Izvorni znanstveni članak
The Prevalence of Systemic Diseases and Medications in Patients with Oral Lichen Planus
Ivana Canjuga
orcid.org/0000-0001-8076-7591
; Stomatološki fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Marinka Mravak-Stipetić
orcid.org/0000-0001-8845-8603
; Stomatološki fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Božana Lončar
orcid.org/0000-0001-6096-6796
; Stomatološki fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Josipa Kern
orcid.org/0000-0002-0896-3018
; Zavod za medicinsku statistiku, epidemiologiju i medicinsku informatiku, Škola narodnog zdravlja Andrija Štampar, Zagreb, Hrvatska
Sažetak
Lichen planus is a chronic immunologic inflammatory disease that frequently involves oral mucosa. Systemic diseases and medications are considered to be precipitating factors in the development of oral lichen planus. Objective: The purpose of this study was to examine the prevalence of systemic diseases and medications in patients with oral lichen planus (OLP) and to determine possible causal relationship. Materials and methods: Retrospective data included medical records of 145 patients, 104 women and 41 men who were referred to the Department of Oral Medicine. All patients had clinical and histopathological criteria fulfilled for diagnosis of oral lichen planus. Data were collected for the period of two years (autumn 2007- autumn 2009). These data were compared with the prevalence of systemic diseases in patients with oral leukoplakia (LPL) and general Croatian population according to the national statistical register. The same comparison was made for the used medications. Obtained data were analyzed by use of χ2 test with level of significance p<0,05. Results: Systemic diseases associated with OLP were found in 77.9% of patients. The most frequent disease was hypertension. Frequency of systemic diseases between patients with OLP and LPL has shown statistically significant difference. Conclusion: Increased prevalence of hypertension among OLP patients in comparison to the prevalence in the general population can not be interpreted as the etiological factor for the development of OLP since hypertension is the most prevalent disease in general population.
Ključne riječi
Lichen Planus, Oral; Leukoplakia; Hypertension; Diseases, Systemic
Hrčak ID:
55643
URI
Datum izdavanja:
18.6.2010.
Posjeta: 2.899 *