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Orofacial Granulomatosis: Case Report

Vlaho Brailo ; Department of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, Croatia
Vanja Vučićević Boras orcid id orcid.org/0000-0003-1651-8069 ; Department of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, Croatia
Sven Seiwert ; Department of Pathology, Zagreb University Hospital Center; Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Vedran Tomašić ; Clinical Department of Gastroenterology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Iva Bakale ; Department of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, Croatia
Danica Vidović Juras ; Department of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, Croatia
Suzana Ljubojević Hadžavdić ; Clinical Department of Dermatology and Venereology, Zagreb University Hospital Center, Zagreb, Croatia


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Abstract

An 18-year-old girl was referred to the Department of Oral Medicine with upper lip swelling. She was in good general health and laboratory tests were within the normal range. Histopathologic diagnosis did not reveal the presence of granulomas. This is consistent with the finding that 30% of patients with orofacial granulomatosis do not have granulomas on their biopsies. The patient was treated with intralesional steroids once a week for three weeks. The lesion subsided, but not completely, and recurred partially after ketchup intake. This case report highlights the fact that in every patient with non-odontogenic facial or oral swelling, systemic diseases such as sarcoidosis, Crohn’s disease, tuberculosis, etc. must be excluded. Furthermore, it is not unusual that in patients with orofacial granulomatosis, noncaseating granulomas are absent in the histopathologic finding.

Keywords

Granulomatosis, orofacial – diagnosis; Granulomatosis, orofacial – therapy; Case reports

Hrčak ID:

148974

URI

https://hrcak.srce.hr/148974

Publication date:

1.11.2015.

Article data in other languages: croatian

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