Original scientific paper

Histological and biochemical alterations in rat's liver and kidney induced by thorium nitrate

Jai Raj Behar ; Industrial Toxicology Research Centre, Lucknow, India
S. K. Tandon ; Industrial Toxicology Research Centre, Lucknow, India
A. K. Mathur ; Industrial Toxicology Research Centre, Lucknow, India
Satya V. Chandra ; Satya V. Chandra

Abstract

The histopathological and biochemical alterations in rat's liver and kidney induced by daily intraperitoneal administration of thorium nitrate were studied. The activity of alkaline phosphatase and adenosine triphosphatase was found to be inhibited at various intervals and the pathomorphological changes were found to be related to the duration of treatment. The results indicate that the effect of thorium is cumulative and that the biochemical alterations occur prior to histological changes.

Keywords

Hrčak ID:

166948

URI

https://hrcak.srce.hr/166948

Publication date:

29.3.1976.

Article data in other languages: croatian

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