Croatica Chemica Acta, Vol. 28 No. 4, 1956.
Short communication, Note
Synthesis of Some Quaternary Ammonium Salts Derived from Esters of Dihydromuconic Acid
D. Fleš
; Research Department, »Pliva « Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia
A. Markovac-Prpić
; Research Department, »Pliva « Pharmaceutical and Chemical Works, Zagreb, Croatia, Yugoslavia
Abstract
Choline esters of dicarboxylic acids, because of their use as short acting neuromuscular blocking agents, have been in the last few years the subject of wide inivestigations. Bovet and collaborators have studied the relationship between the chain length of ailiphatic dicarboxylic acids and the curariform activity. They found that the activity increases if the length of the chain increases from oxalic to succinic acid, but further lengthening of the chain decreases the paralysing activity. They also claimed that the double bond had no significant influence on the curariform activity.
Keywords
Hrčak ID:
246836
URI
Publication date:
6.2.1957.
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