Original scientific paper

https://doi.org/10.20471/acc.2020.59.04.06

Factors Associated with Depression in Patients with Schizophrenia

Boris Golubović ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Psychiatry, Clinical Centre of Vojvodina, Novi Sad, Serbia
Zoran Gajić ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Psychiatry, Clinical Centre of Vojvodina, Novi Sad, Serbia
Olga Ivetić ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Psychiatry, Clinical Centre of Vojvodina, Novi Sad, Serbia
Jovan Milatović ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Psychiatry, Clinical Centre of Vojvodina, Novi Sad, Serbia
Petar Vuleković ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Neurosurgery, Clinical Centre of Vojvodina, Novi Sad, Serbia
Đula Đilvesi ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Neurosurgery, Clinical Centre of Vojvodina, Novi Sad, Serbia
Sonja Golubović ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Centre of Vojvodina, Novi Sad, Serbia
Filip Vrban ; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; University of Health Applied Sciencies, Zagreb, Croatia
Ante Subašić ; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Lukas Rasulić orcid.org/0000-0002-5674-0425 ; University of Belgrade, Faculty of Medicine, Belgrade, Serbia; Division of Peripheral Nerve Surgery, Functional Neurosurgery and Pain Management Surgery, Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia

Abstract

The aim of this study was to analyze risk factors present in schizophrenic patients
with depressive symptomatology. The sample comprised of 76 respondents diagnosed with schizophrenia.
In the study, we used the Positive and Negative Syndrome Scale (PANSS) and Calgary Depression
Scale for Schizophrenia. The prevalence of depression was estimated to be 30%. The mean
scores on the negative subscale of the PANSS were significantly higher in patients with schizophrenia
and depression compared to control group (U=3.64, p=0.00), and so were those on the General Psychopathology
Scale (U=4.91, p=0.00). Socio-demographic factors were identified as important factors
(p<0.05). Personal and environmental factors such as loneliness, immediate social environment, social
support and isolation were statistically significantly different between the groups (p<0.05). There was
a correlation of poor compliance with psycho-pharmacotherapy, increased number of hospitalizations
and shorter remission period with the severity of clinical presentation (p<0.05). Since the presence of
these factors is associated with depression in schizophrenia, their early detection in clinical practice is
vital to ensure timely prevention of the development of depressive symptomatology.

Keywords

Schizophrenia; Depression; Sociodemographic factors

Hrčak ID:

253737

URI

https://hrcak.srce.hr/253737

Publication date:

1.12.2020.

Article data in other languages: croatian

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