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Acta clinica Croatica, Vol. 60. No. Supplement 1, 2021.

Original scientific paper

https://doi.org/10.20471/acc.2021.60.s1.02

FRAX in Haemodialysis Patients: Preliminary Results

Draško Pavlović orcid id orcid.org/0000-0002-2380-869X ; Polyclinic for Internal Medicine and Dialysis, B. Braun Avitum, Zagreb, Croatia
Sonja Dits ; Polyclinic for Internal Medicine and Dialysis, B. Braun Avitum, Zagreb, Croatia
Dijana Knežević Strinavić ; General Hospital Nova Gradiška, Department of Internal medicine, Haemodialysis Unit, Nova Gradiška, Croatia
Slava Doko ; Health Center Zagreb - East Haemodialysis Center, Zagreb, Croatia
Ivančica Hršak ; Polyclinic for Internal Medicine and Dialysis, B. Braun Avitum, Zagreb, Croatia
Boris Kudumija ; Polyclinic for Internal Medicine and Dialysis, B. Braun Avitum, Zagreb, Croatia

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Abstract

The incidence of bone fractures is several times higher in haemodialysis (HD)
patients than in the general population. FRAX is a fracture risk evaluation tool and shows a 10-year
probability of bone fracture. The aim of this study was to evaluate the FRAX score in haemodialysis
patients.
The study included 214 HD patients (81 female). We used the following calculation tool:
https://www.sheffield.ac.uk/FRAX/?lang=cr. Increased risk for major fracture (MF) was defined as
FRAX > 20% and for hip fracture (HF) > 3%.
If renal osteodystrophy (ROD) is defined as primary osteoporosis, the average FRAX value for
MF is 7.4 ± 6.4% and for HF 3.5 ± 4.1%, and as secondary osteoporosis, the average FRAX value for
MF is 10.3 ± 8.4 %, for HF 5.4 ± 5.9%. 13.6% of patients or 49.1% had an increased risk for MF
or HF if ROD was defined as secondary osteoporosis. If it was defined as primary osteoporosis, the
results were 7.1% for MF or 39.2% for HF. In women, FRAX values were significantly higher for both
HF and MF.
According to our preliminary results, a large number of patients have an increased FRAX score
risk, especially if we define ROD as secondary osteoporosis. The FRAX score is higher in women.

Keywords

FRAX; Haemodialysis; Bone fracture

Hrčak ID:

260248

URI

https://hrcak.srce.hr/260248

Publication date:

1.1.2021.

Article data in other languages: croatian

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