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Case report

https://doi.org/10.20471/acc.2021.60.02.23

Atypical MRI Findings in Cerebral Adrenoleukodystrophy: a Case Report

Koray Koç ; Antalya Ataturk State Hospital, Department of Radiology, Antalya, Turkey
Arzu Canan ; University of Texas Southwestern Medical Center at Dallas, Department of Radiology, Dallas, Texas, USA
Pınar Koç ; Antalya Ataturk Training and Research Hospital, Department of Radiology, Antalya, Turkey
Kamil Karaali ; Akdeniz University, Faculty of Medicine, Department of Radiology, Antalya, Turkey
Özgür Duman ; Akdeniz University, Faculty of Medicine, Department of Child Neurology, Antalya, Turkey
Utku Şenol ; Akdeniz University, Faculty of Medicine, Department of Radiology, Antalya, Turkey


Full text: english pdf 320 Kb

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Abstract

Adrenoleukodystrophy is a rare X-linked hereditary disease that results in accumulation
of very-long-chain fatty acids in all body tissues, thus causing demyelination of the white
matter. Magnetic resonance imaging (MRI) is a reliable radiological modality to demonstrate the
extension of brain lesions and severity of the disease. In the classic form, the parieto-occipital white
matter is affected. Besides, atypical MRI findings such as primary frontal lobe involvement are rarely
described. We report a case of adrenoleukodystrophy presenting with rare MRI findings such as bilateral
symmetric frontal lobe white matter changes suggesting anterior predominance.

Keywords

Adrenoleukodystrophy, Magnetic resonance imaging, Very-long-chain fatty acids, White matter

Hrčak ID:

263810

URI

https://hrcak.srce.hr/263810

Article data in other languages: croatian

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