ADMET and DMPK, Vol. 10 No. 2, 2022.
Review article
https://doi.org/10.5599/admet.1137
Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
Matthias Fellner
; University of Otago, Dunedin, New Zealand
Abstract
There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.
Keywords
Inhibitor; biofilm; fluorophosphonate
Hrčak ID:
273560
URI
Publication date:
4.3.2022.
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