Original scientific paper

https://doi.org/10.15255/KUI.2021.062

Hemi-synthesis of Thione and Thiol Derivatives from Artemisia judaica L. Essential Oil, and Antimicrobial Tests

Asma Drioueche ; Chemical Engineering Laboratory (LGC), University of Blida1, Faculty of Technology, B. P. 270, Soumaa road, 09000 Blida, Algeria
Hocine Boutoumi ; Chemical Engineering Laboratory (LGC), University of Blida1, Faculty of Technology, B. P. 270, Soumaa road, 09000 Blida, Algeria
Nabahat Benmansour ; University of Blida1, Faculty of Natural and Life Sciences, Department of Biology, B. P. 270, Soumaa Road, 09000 Blida, Algeria
Hichem Lettreuch ; Materials and Environment Laboratory, University Yahia Fares of Médéa, 26 000 Médéa, Algeria

Abstract

The applications of organosulfur compounds, especially thioketones are varied which concerns both synthetic and biological chemistry. In this context, from the essential oil of Artemisia judaica L., extracted by hydrodistillation, and consisting mainly of piperitone (91.77 %), thione, and thiol derivatives were hemi-synthesized via a thionylation reaction byphosphorus pentasulphide (P₂S₅). The possible thione-thiol tautomerism in solution followed spectrophotometrically revealed the predominance of thiol form in solution. The antimicrobial activity of essential oils showed that the thionylation of essential oil caused a considerable increase in antimicrobial activity in particular against Escherichia coli.




This work is licensed under a Creative Commons Attribution 4.0 International License.

Keywords

Artemisia judaica L.; essential oil; thionylation; tautomerism; antimicrobial activity

Hrčak ID:

277636

URI

https://hrcak.srce.hr/277636

Publication date:

15.5.2022.

Article data in other languages: croatian

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