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Acta clinica Croatica, Vol. 61. No. Supplement 1, 2022.

Review article

https://doi.org/10.20471/acc.2022.61.s1.09

Prothrombin Complex Concentrate in Emergency Department

Višnja Nesek Adam orcid id orcid.org/0000-0002-6521-4136 ; Emergency Department, Clinical Hospital Sveti Duh, Zagreb, Croatia; Faculty of Dental Medicine and Health, Osijek, Croatia; Libertas Interantional University, Zagreb, Croatia
Ingrid Bošan-Kilibarda ; Croatian Institute for Emergency Medicine, Croatia

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Abstract

Coagulation abnormalities are common in bleeding or critically ill patient and
hemostatic management remains a major challenge for the emergency physician. Management of
bleeding patients consists of bleeding control, restoration of blood volume, and correction of any associated
coagulopathy. Traditionally, the fresh frozen plasma (FFP) is used for correction of coagulopathy
to manage and prevent bleeding, but today Prothrombin complex concentrates (PCCs) offer
an attractive alternative because they offers a number of advantages over FFP, including lower infusion
volume, rapid IN R normalization, faster availability, lack of blood group specificity, and better
safety profile. The aim of the present review is to provide an short overview about using PCC, their
indication, efficacy and safety in different bleeding setting’s.

Keywords

bleeding; emergency department; prothrombin complex concentrates

Hrčak ID:

281189

URI

https://hrcak.srce.hr/281189

Publication date:

1.6.2022.

Article data in other languages: croatian

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