Review article
Laryngeal transplantation
Dražen Shejbal
; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital, Zagreb, Croatia
Mirko Ivkić
; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital, Zagreb, Croatia
Vladimir Bedeković
; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital, Zagreb, Croatia
Livije Kalogjera
; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital, Zagreb, Croatia
Renato Janušić
; Department of Head and Neck Tumors, University Hospital for Tumors, Zagreb, Croatia
Abstract
Laryngeal transplantation is not a new concept. Experiments with reinnervation, revascularisation, immunosupression and preservation started in the late 1950s. The impression after the first successful transplantation was as follows: all expected complications were successfully overcome and the expected failures did not occur. This report will discuss ethical and tehnical considerations of laryngeal transplanatation and risk of cancer reccurrence due to immunosuppression. Laryngeal organ transfer holds the best promise for preserving the quality of life in patients who have lost laryngeal function.
Keywords
laryngeal transplantation; reinnervation; revascularistaion; ethical consideration
Hrčak ID:
281803
URI
Publication date:
3.12.2003.
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