Original scientific paper

https://doi.org/10.2478/v10184-010-0001-x

Biological activity of red alga Laurencia brandenii

Aseer Manilal ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
Sugathan Sujith ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
Balu Sabarathnam ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
George S. Kiran ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
Joseph Selvin ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
Chippu Shakir ; Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, India
Aaron P. Lipton ; Central Marine Fisheries Research Institute, Vizhinjam 695 521, Thiruvananthapuram, India

Abstract

The marine red alga Laurencia brandenii collected from the southwest coast of India (Indian Ocean) was extracted and fractioned using column chromatography. The individual fractions were evaluated in vitro via antimicrobial activity against six species of Microbial Type Culture Collection and three species of clinical human pathogens, antipest activity on Sitophilus oryzae, maggoticidal activity against and instar larvae of Sarcophaga sp. and termiticidal activity against Microtermes obesi. It was found that the fraction eluted using petroleum ether:chloroform (6:4) exhibited broader biological activities. The phyco-constituents of the active fraction were identified by gas chromatography- -mass spectrometry (GC-MS) analysis. The GC-MS profile of the active fraction revealed that the main constituent was octadecadienoic acid (49.75%) followed by n-hexadecanoic acid (14.24%), which might have a functional role in the biological activities. The overall activity profile envisages that these bioactive compounds from L. brandenii could be utilized as a renewable natural resource for the development of novel environmental-compatible formulations for the control of human pathogens, pests, termites and maggots.

Keywords

Alga; Laurencia brandenii; antimicrobial activity; antipest activity; maggoticidal activity; termiticidal activity; larva; Sarcophaga; octadecadienoic acid; n-hexadecanoic acid

Hrčak ID:

66278

URI

https://hrcak.srce.hr/66278

Publication date:

5.4.2011.

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