Preliminary communication
Osteolytic Skull Metastasis with Dural Involvement from a Papillary Thyroid Carcinoma
Karlo Houra
Majda Vučić
Hrvoje Čupić
Damir Kovač
Vatroslav Čerina
Abstract
Skull metastatic tumors are relatively rare medical entities and originate most often from the lungs, breast or prostate.
We report a case of a 76-year-old woman who presented with a bulging, well-circumscribed mass on the right side of
the forehead. Neuroimaging of the cranium detected an osteolytic lesion measuring 7 cm in the largest diameter while
propagating outwards and intracranially. A thorough medical history revealed that patient had undergone surgery for
invasive breast ductal carcinoma and also for a well-differentiated thyroid carcinoma 13 years ago. Considering patients
medical history metastatic breast carcinoma was suspected. After a frontal craniotomy the tumour tissue was totally
resected. Histological examination revealed metastatic papillary carcinoma characterized by ground-glass nuclei with
intranuclear pseudo inclusion and nuclear grooves. We report clinical and neuroradiological features of this uncommon
lesion and discussed the differential diagnosis of skull osteolytic lesion together with the treatment management.
Keywords
distant metastasis; osteolytic lesion; papillary thyroid carcinoma; skull
Hrčak ID:
72198
URI
Publication date:
30.9.2011.
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