Original scientific paper

Endoskopska prosudba želučane sluznice nakon oralnog davanja ibuprofena u pasa.

Rajah Arunachalam Ramprabhu ; Centre of Advanced Studies in Clinical Medicine and Therapeutics, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Vepery, India
Sethupandian Prathaban ; Centre of Advanced Studies in Clinical Medicine and Therapeutics, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Vepery, India
Ayyanampakkam Pandurangan Nambi ; Centre of Advanced Studies in Clinical Medicine and Therapeutics, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Vepery, India
Balasubramanian Nagarajan ; Centre of Advanced Studies in Clinical Medicine and Therapeutics, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Vepery, India
Periasamy Dhanapalan ; Centre of Advanced Studies in Clinical Medicine and Therapeutics, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Vepery, India

Abstract

Istraživanja su provedena s ciljem da se utvrde promjene na sluznici želuca u pasa nakon primjene terapijskih i toksičnih doza ibuprofena. Tako su petog i osmog dana nakon primjene provedene kliničke, hematološke i endoskopske pretrage pasa. U pasa je endoskopijom utvrđena jača kongestija sluznice petog te manje krvareći vrijedovi osmoga dana nakon primjene terapijskih doza ibuprofena. Primjenom toksičnih doza prouzrokovalo se jače krvarenje sluznice već petoga dana. Na osnovi istraživanja autori zaključuju da su psi osjetljiviji na ibuprofen u odnosu na čovjeka te da se taj lijek može primjenjivati samo uz najveći oprez.

Keywords

pas; ibuprofen; toksičnost; endoskopija

Hrčak ID:

83119

URI

https://hrcak.srce.hr/83119

Publication date:

18.2.2001.

Article data in other languages: english

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