Original scientific paper
Evaluation of Salivary Calcium and Phosphorous Concentration Before and After Chewing CPP-ACP Containing Chewing Gum
Gauri Kakatkar
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Ramesh Nagarajappa
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Nagesh Bhat
; Department of Public Health Dentistry, Darshan Dental College and Hospital, Loyara, Udaipur-313011, Rajasthan, India
Archana Sharda
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Kailash Asawa
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Sagar Jalihal
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Mridula Tak
; Department of Public Health Dentistry, Pacific Dental College and Hospital, Debari, Udaipur-313024, Rajasthan, India
Abstract
Objective: To estimate the salivary concentration of calcium and phosphorous before and after chewing sugar free chewing gum containing Casein phosphopeptide-Amorphous calcium phosphate
(CPP-ACP) namely RecaldentTM and to determine the extent and duration to which the salivary levels of calcium and phosphorus remain retained in saliva after chewing the CPP-ACP containing gum. Materials and Method: A non-randomized clinical trial was conducted among 30 randomly selected students aged 18 – 25 years. Unstimulated saliva was collected by draining method before and at different intervals after chewing CPP-ACP chewing gum for 20 minutes. These samples were tested for calcium and phosphorous concentration. Data were analyzed using SPSS version 17 software using Repeated measure Anova and Students paired t-test and percentage difference. Results: The mean calcium concentration of saliva increased significantly immediately after (Ai) chewing CPP-ACP containing chewing gum with the mean difference of 22% when compared to the baseline (B). A significant increase in the calcium concentration of saliva as compared to the baseline (B) was observed for up to 2 hours after chewing the gum, whereas a decrease in the phosphorus concentration in saliva for up to 1 hour after chewing the gum was observed when compared to baseline (B). Conclusion - CPP as an ACP carrier significantly increases the calcium concentration of the saliva, thereby facilitating remineralization.
Keywords
CPP-ACP; Casein Phosphopeptide-Amorphous Calcium Phosphate Nanocomplex; Chewing Gum; Calcium; Phosphorus; Saliva
Hrčak ID:
84241
URI
Publication date:
10.7.2012.
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