Original scientific paper

Effect of sublethal lead concentrations in feed on δ−aminolevulinic acid dehydratase activity in young carp.

Emil Srebočan orcid.org/0000-0001-8110-1265 ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Jelena Pompe-Gotal ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Andreja Prevendar-Crnić ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Zvjezdana Špacir ; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia

Abstract

The δ−aminolevulinic acid dehydratase (ALA-D) activity was examined in two groups of carp (Cyprinus carpio L.) exposed to sublethal lead concentrations (1.3 and 2.6 ppm) for 60 days. There was no statistically significant change in ALA-D activity at one-month lead exposure. After two months, ALA-D activity was decreased in both experimental groups of fish compared with the control group. The decrease in ALA-D activity reached statistical significance (P<0.05) in the group of fish administered 2.6 ppm lead in feed. ALA-D is probably the best indicator of fish exposure to lead. Feed is an important source of ground-fish lead contamination that can compromise fish health and reduce their productivity.

Keywords

lead; δ−aminolevulinic acid dehydratase (ALA-D); sublethal toxicity; carp

Hrčak ID:

92947

URI

https://hrcak.srce.hr/92947

Publication date:

19.12.2001.

Article data in other languages: croatian

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