Croatica Chemica Acta, Vol. 86 No. 4, 2013.
Original scientific paper
https://doi.org/10.5562/cca2338
On Map Representations of DNA
Milan Randić
; Laboratory for Chemometrics, National Institute of Chemistry, Hajdrihova 19, Ljubljana, Slovenia
Boris Horvat
; Institute of Mathematics, Physics and Mechanics, University of Ljubljana, Slovenia; University of Primorska, Koper, Slovenia; Abelium, d.o.o. Ljubljana, Slovenia
Gašper Jaklič
; Institute of Mathematics, Physics and Mechanics, University of Ljubljana, Slovenia
Dejan Plavšić
; NMR Center, Institute Rudjer Bošković, Bijenička cesta 54, Zagreb, Croatia
Tomaž Pisanski
; Institute of Mathematics, Physics and Mechanics, University of Ljubljana, Slovenia; University of Primorska, Koper, Slovenia
Abstract
We have constructed graphical (qualitative and visual) representations of DNA sequences as 2D
maps and their numerical (quantitative and computational) analysis. The maps are obtained by transforming
the four-letter sequences (where letters represent the four nucleic bases) via a spiral representation
over triangular and square cells grids into a four-color map. The so constructed maps are then represented
by distance matrices. We consider the use of several matrix invariants as DNA descriptors for determining
the degree of similarity of a selection of DNA sequences. (doi: 10.5562/cca2338)
Keywords
DNA graphical representation; virtual genetic code; numerical representation; four color map; distance matrix of DNA; DNA similarity; DNA descriptors
Hrčak ID:
112796
URI
Publication date:
16.12.2013.
Visits: 1.861 *