Professional paper

Verruciform Xanthoma: Report of Three Cases

Kittipong Dhanuthai
Kitti Torrungruang

Abstract

Verruciform xanthoma is a relatively uncommon mucocutaneous lesion. Most of the reported cases occur in masticatory oral mucosa, especially the gingiva. This article reports three cases of verruciform xanthoma, all of which were located in the palatal gingiva. The lesions were small and painless. Two were papillary lesions, and the other was cauliflower-like. Histological examinations revealed papillomatosis and acanthosis associated with xanthoma cell aggregation within connective tissue papillae. Xanthoma cells were positive to CD 68 antibody, indicating a macrophage origin. All lesions were treated by conservative surgical excision, and no recurrence was observed. Differential diagnosis and pathogenesis of verruciform xanthoma are discussed. In some cases, its clinical appearance may resemble verrucous carcinoma or squamous cell carcinoma. Therefore, clinicians should be acquainted with this lesion to avoid an unnecessary excessive surgical intervention.

Keywords

Xanthomatosis; Gingiva; Melanosis; Papilloma

Hrčak ID:

12549

URI

https://hrcak.srce.hr/12549

Publication date:

15.6.2007.

Article data in other languages: croatian

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