Professional paper
https://doi.org/10.15836/ccar2015.283
Angioedema Caused by Agents Acting on the Angiotensin System
Tanja Batinac
; University Hospital Centre Rijeka, Rijeka, Croatia
Željko Plazonić
; University Hospital Centre Rijeka, Rijeka, Croatia
Marija Bukvić
; University Hospital Centre Rijeka, Rijeka, Croatia
Abstract
Rennin angiotensin system (RAS) blockers are commonly used drugs with proven benefits for cardiovascular and renal diseases. There are four classes of drugs acting on the angiotensin system, the most commonly used being angiotensin converting enzyme inhibitors (ACEI) followed by angiotensin receptor blockers (ARB). These drugs are generally considered safe and effective in the majority of patients, but in some cases adverse drug reactions may occur (ADRs). Angioedema
resulting from RAS blocker treatment is a rare but potentially life-threatening event, and we should keep in mind that in recent years the exponential growth of the use if RAS blockers has been evident
worldwide, resulting in increased prevalence of angioedema induced by RAS blockers in these patients.
Keywords
adverse drug reaction; angioedema; angiotensin converting enzyme inhibitors; renin angiotensin system blockers
Hrčak ID:
153260
URI
Publication date:
10.1.2016.
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