Original scientific paper
The effect of lead on protein and lactate dehydrogenase activity in hepatic slices cultured in vitro
E.J. Kucharz
; Department of Clinical Chemistry and Laboratory Diagnostics and Department of Pathology, Silesian School of Medicine, Katowice, Poland
B. Stawiarska-Pieta
; Department of Clinical Chemistry and Laboratory Diagnostics and Department of Pathology, Silesian School of Medicine, Katowice, Poland
Abstract
Slices of foetal and adult liver were cultured in vitro with various concentrations of Iead ions. A decrease in protein content and an increase in lactate dehydrogenase activity in the culturing medium were found. The changes were dose-dependent, and the foetal liver tissue was found to be more susceptible to the effect of lead than the tissue of adult rats.
Keywords
Hrčak ID:
153812
URI
Publication date:
24.2.1987.
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