Acta Botanica Croatica, Vol. 46 No. 1, 1987.
Original scientific paper
The Cytotoxicity of Dichlorvos and its Commercial Formulations on Yeast Saccharomyces cerevisiae
Magdalena Eger
; Hrvatska
Nada Horš
; Hrvatska
Vesna Birtić
; Hrvatska
Abstract
The cytotoxic effects of organophosphorus compound dichlorvos and of its commercial formulations Nuvan — 50 and Nogos — 50, both produced and in use in Yugoslavia, were comparatively studied. Saccharomyces cerevisiae N 123 yeast strain served as a test organism.
Yeasts were incubated in a complete nutrient medium containing the pesticide in a concentration range from 0.125 to 12.0 mg/ml of active substance. The cytotoxic effect was determined as the degree of inhibited cell division during and after 26-hour incubation at 28°C.
According to results the original form of dichlorvos is more toxic than the two commercial formulations, and so is Nuvan-50 compared to Nogos-50. In our experimental conditions no increase of tolerance of the microorganism to the pesticide or the reversibility of the effect after treatment with high pesticide concentrations could be established.
It may be concluded that the effect of the active substance, dichlorvos, is modified in formulations more in terms of intensity rather than in the mode of action
Keywords
Hrčak ID:
159300
URI
Publication date:
31.12.1987.
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