Professional paper

Preemptive kidney transplantation from living donor

Dean Markić orcid.org/0000-0001-5696-0850 ; University Hospital Rijeka, Department of Urology, Rijeka, Croatia
Josip Španjol ; University Hospital Rijeka, Department of Urology
Kristian Krpina ; University Hospital Rijeka, Department of Urology
Antun Gršković ; University Hospital Rijeka, Department of Urology
Dražen Rahelić ; University Hospital Rijeka, Department of Urology
Mauro Materljan ; University Hospital Rijeka, Department of Urology
Marin Trošelj ; University Hospital Rijeka, Department of Urology
Martina Pavletić Peršić ; University Hospital Rijeka, Department of Nephrology, Dialysis and Kidney Transplantation
Lidija Orlić ; University Hospital Rijeka, Department of Nephrology, Dialysis and Kidney Transplantation
Ivan Bubić ; University Hospital Rijeka, Department of Nephrology, Dialysis and Kidney Transplantation
Andrea Arefijev ; Faculty of Medicine, University of Rijeka, Rijeka, Croatia
Sanjin Rački orcid.org/0000-0002-3736-0929 ; University Hospital Rijeka, Department of Nephrology, Dialysis and Kidney Transplantation

Abstract

Pre-emptive kidney transplantation is the type of transplantation that is performed before starting dialysis. It allows a better quality of life to the patient and significant reduction of costs in comparison with dialysis, and also is connected with higher survival rate of graft and patient. We present a 26-year-old patient diagnosed with chronic kidney disease (CKD) due to IgA nephropathy. His kidney function, despite of immunosuppressive therapy, gradually decreased in time but an onset of acute enterocolitis has lead to significant and permanent deterioration of kidney function with the forthcoming need for renal replacement therapy. His mother was accepted as a living kidney donor. The left kidney of the mother was transplanted to the right iliac fossa of the patient. The operation went without any complications. The postoperative course was uneventful with induction therapy with monoclonal antibody against interleukin 2 receptor and standard triple immunosuppressive therapy consisting of corticosteroid, mycophenolat mofetil and tacrolimus. One year after the transplantation, the patient has a good functioning kidney transplant without any surgical or immunological complications. Conclusively, pre-emptive kidney transplantation is an effective treatment for patients with end-stage renal disease and it should be recommended to all patients where this type of treatment is possible.

Keywords

preemptive transplantation; living donor; chronic kidney disease; IgA nephropaty

Hrčak ID:

159883

URI

https://hrcak.srce.hr/159883

Publication date:

7.6.2016.

Article data in other languages: croatian

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