Medicina Fluminensis, Vol. 52 No. 3, 2016.
Other
https://doi.org/10.21860/52;3_430
A case of residual melanoma of the finger
Koviljka Matušan Ilijaš
; Zavod za patologiju i patološku anatomiju, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Boštjan Luzar
; Inštitut za patologijo, Medicinska fakulteta, Univerza v Ljubljani,
Ita Hadžisejdić
; Zavod za patologiju, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Nives Jonjić
; Zavod za patologiju i patološku anatomiju, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Abstract
Objective: The objective of this paper is to present a diagnostic procedure in a case of residual melanoma of the finger. Case report: We received a dome shaped, skin specimen from a forty-four year old man. The skin sample was taken from the fourth finger of his right hand and it was 1 cm in diameter. The skin coloured lesion was serially sectioned and submitted for histopathologic analysis. Microscopic examination showed that it was melanocytic lesion and considering it had no epidermal component, additional molecular analyses were needed to exclude a clear cell sarcoma. A diagnosis of residual melanoma was made, from subsequently received clinical data, however there was no accompanying histopathological analysis from the first excision. Conclusion: A histopathological diagnosis, in general, as well as in the case of melanoma may be difficult due to the lack of clinical data. Contemporary histopathological diagnostics has a good support tools for establishing an accurate diagnosis, which governs the further diagnostic and therapeutic patient’s protocol. However, clinical dermatological examination of doubtful pigmented lesions, complemented by histopathologic diagnostics is a crucial step important for timely diagnosis in order to avoid delay in the therapy which is important for patient’s disease outcome.
Keywords
clear cell sarcoma; differential diagnosis; fluorescence in situ hybridization; immunohistochemistry; melanoma
Hrčak ID:
163958
URI
Publication date:
1.9.2016.
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