Original scientific paper
Histological and biochemical alterations in rat's liver and kidney induced by thorium nitrate
Jai Raj Behar
; Industrial Toxicology Research Centre, Lucknow, India
S. K. Tandon
; Industrial Toxicology Research Centre, Lucknow, India
A. K. Mathur
; Industrial Toxicology Research Centre, Lucknow, India
Satya V. Chandra
; Satya V. Chandra
Abstract
The histopathological and biochemical alterations in rat's liver and kidney induced by daily intraperitoneal administration of thorium nitrate were studied. The activity of alkaline phosphatase and adenosine triphosphatase was found to be inhibited at various intervals and the pathomorphological changes were found to be related to the duration of treatment. The results indicate that the effect of thorium is cumulative and that the biochemical alterations occur prior to histological changes.
Keywords
Hrčak ID:
166948
URI
Publication date:
29.3.1976.
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