Original scientific paper
The influence of the vitamin d and phosphate content of the diet on calcium and strontium absorption from the gastrointestinal tract
Krista Kostial
; Institute for Medical Research, Yugoslav Academy of Sciences and Arts, Zagreb
Tea Maljković
; Institute for Medical Research, Yugoslav Academy of Sciences and Arts, Zagreb
Nevenka Gruden
; Institute for Medical Research, Yugoslav Academy of Sciences and Arts, Zagreb
A. Duraković
; Institute for Medical Research, Yugoslav Academy of Sciences and Arts, Zagreb
Abstract
The effect of various amounts of phosphates and vitamin D in the diet on calcium and strontium absorption was studied in rats. The animals were kept on experimental diet for 6 days and during that period they received radioactive isotopes of calcium (45Ca) and strontium (85Sr) in drinking water. Skeletal retention of radioactive calcium and strontium was determined. Increased dietary phosphates (from 0.5 to 1.2% P) were found to cause a reduction in the retention of radioactive calcium and strontium after oral administration of isotopes. The effect of phosphates proved to be much stronger on strontium than on calcium absorption. This is in agreement with our earlier results. The effect of phosphates on calcium and strontium metabolism proved independent of the vitamin D content in the diet if this content ranged from 200 to 800 I. U. per 100 g of dry food.
Keywords
Hrčak ID:
176841
URI
Publication date:
20.3.1968.
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