Professional paper
Effect of Vipera ammodytes ammodytes venom on the isolated heart
I. Ivančević
; Farmakološki institut Medicinskog fakulteta u Zagrebu
Abstract
Vipera ammodytes ammodytes venom produces a great variety of histopathological changes in the isolated and perfused frog and guinea pig heart, corresponding to the complexity of snake venom. These changes suggest the conclusion that the high-molecular protein-like compounds of the venom, e. g. the genuine toxins are mainly responsible for the heart effects. The small-molecular constituents as histamine, 5-0H-tryptamine and acetylcholine play apparently herein a less important role. However, further investigations with separated fractions of the venom are desirable.
Keywords
Hrčak ID:
181438
URI
Publication date:
13.3.1963.
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