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Professional paper

MYOCARDIAL INFARCTION AS A CONSEQUENCE OF CHILDHOOD POLYARTERITIS NODOSA – CASE REPOR

Viktorija Ana Buljević
Matias Trbušić
Diana Delić-Brkljačić
Ivan Malčić


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Abstract

Polyarteritis nodosa (PAN) is a systemic vasculitis histologically characterized by necrotic lesions of small and medium-
sized arteries occurring mostly in their bifurcations. PAN is a multi-organ disorder that aff ects numerous visceral
arteries and leads to infl ammation and necrosis, which may result in ischemia of vital organs. Th e etiology of the disease
is unknown. It occurs in four forms - cutaneous (most common), classic, systemic, and microscopic. PAN preferably
aff ects the renal and coronary arteries. Th e most common fi ndings in the aff ected blood vessels are aneurysm, thrombosis,
and stenosis. Cardiac complications are rare in children, but 35% of patients develop a complication in adulthood. Th e
most common complication in adulthood is cardiac decompensation, which can be explained as a consequence of longstanding
hypertension and changes in coronary blood vessels. Th e incidence of myocardial infarction is low, particularly
in young patients. Th is paper describes a 25-year-old patient with acute myocardial infarction accompanied by changes
in the coronary blood vessels and persistent arterial hypertension as a result of PAN diagnosed in childhood.

Keywords

Polyarteritis nodosa – complications, diagnosis, drug therapy; Myocardial infarction – diagnosis, etiology, therapy; Coronary stenosis – etiology, radiography, therapy; Hypertension – etiology, drug therapy; Coronary angiography; Stents

Hrčak ID:

182819

URI

https://hrcak.srce.hr/182819

Publication date:

28.12.2016.

Article data in other languages: croatian

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