Conference paper

Dissolution of Calcium Hydroxylapatite and its Application to Biological Demineralization

Joergen Christoffersen ; Dept. of Chemistry, Panum Institute University of Copenhagen Blegdamsvej 3, DK-2200 Copenhagen N, Denmark
Margaret Ruth Christoffersen ; Dept. of Chemistry, Panum Institute University of Copenhagen Blegdamsvej 3, DK-2200 Copenhagen N, Denmark
Joop Arends ; Laboratory for Materia Technica, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands

Abstract

Several aspects of the study of the rate of dissolution of
calcium hydroxylapatite in aqueous solution are discussed. From
a chemical point of view, this system provides the possibility to
study the chemical processes taking place at the crystal surface
during the dissolution process, both in the pure system and in
systems containing foreign substances. From a biological point
of view, the study has led to a model for the formation of subsurface
lesions in tooth enamel. An approach to a model for demineralization
of bone tissue comes from the sfudy of the effect
of biologically relevant molecules on the dissolution process in
vitro. Citrate ions are found to inhibit the dissolution process at
low concentration, but accelerate this process at higher concentrations,
where considerable complexing with calcium ions occurs.

Keywords

Hrčak ID:

194196

URI

https://hrcak.srce.hr/194196

Publication date:

9.11.1983.

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