Conference paper

Hydrodynamic Properties of Micelles of Dihydroxy Bile Salts: Sodium Taurodeoxycholate and Sodium Glycodeoxycholate

Josip P. Kratohvil ; Department of Chemistry and Institute of Colloid and Surface Science, Clarkson College of Technology, Potsdam, New York 13676
Tejraj M. Aminabhavi ; Department of Chemistry and Institute of Colloid and Surface Science, Clarkson College of Technology, Potsdam, New York 13676
Wan P. Hsu ; Department of Chemistry and Institute of Colloid and Surface Science, Clarkson College of Technology, Potsdam, New York 13676
Satoru Fujime ; Department of Chemistry, State University of New York at Stony Brook, Long Island, New York 11794, USA
Adam Patkowski ; Department of Chemistry, State University of New York at Stony Brook, Long Island, New York 11794, USA
F. C. Chen ; Department of Chemistry, State University of New York at Stony Brook, Long Island, New York 11794, USA
Benjamin Chu ; Department of Chemistry, State University of New York at Stony Brook, Long Island, New York 11794, USA

Abstract

The dependence of the mutual translational diffusion coefficient
and the sedimentation coefficient on concentration of sodium
taurodeoxycholate in aqueous 0.15 m NaCl solutions at 25 °c indicates
a pronounced increase of the micelle size in the region
between the critical micelle concentration, equal to 0.00082 gcm-3,
and approximately ten times higher concentration. These results
were substantiated by the variation of the Rayleigh ratio of scattered
light. At concentrations of bile salt higher than about 0.008
gcm-3 the hydrodynamic and the thermodynamic interactions dominate
the measured quantities. The quasielastic light scattering
measurements provided the estimates of the polydispersity of the
micelles. The diffusion coefficient of sodium glycodeoxycholate
varied with concentration in a manner similar to that for the
taurine conjugate.

Keywords

Hrčak ID:

194198

URI

https://hrcak.srce.hr/194198

Publication date:

9.11.1983.

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