Review article
https://doi.org/10.15255/KUI.2019.040
Application of Tubular Meso- and Micro-reactors in Organic Synthesis and Photochemistry – Go With the Flow!
Kristina Pavlović
orcid.org/0000-0001-6069-7020
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Ana Ratković
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Martin Gojun
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Anita Šalić
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Bruno Zelić
orcid.org/0000-0003-3210-2960
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Irena Škorić
orcid.org/0000-0002-1563-7261
; Faculty of Chemical Engineering and Technology University of Zagreb, Marulićev trg 19 10 000 Zagreb, Croatia
Abstract
In organic chemistry, more attention is paid to syntheses in micro- and meso-flow systems, which has a number of advantages over batch synthesis. The main advantages of the implementation of organic synthesis in flow reactors are greater efficiency, ecological acceptability and safety. Despite this, the chemistry of flow systems cannot be used as a universal approach for all problems that can be considered by organic synthetic chemists, and prior to the implementation of selected reactions, it is worth considering the cost-effectiveness of batch synthesis. The safety and environmental eligibility of synthesis in flow reactors significantly contributes to the use of a small volume of chemicals and solvents, since the reactions are carried out in micro- or mezo-reactors made, usually, from inert materials. Due to the numerous advantages of organic reactions in flow systems, they are under continuous research. The reaction conditions are optimised in order to increase the efficiency and safety of processes and their magnification.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords
photochemistry; organic synthesis; micro-reactors; application of flow reactors; flow systems
Hrčak ID:
225484
URI
Publication date:
7.10.2019.
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