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Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, Vol. 73 No. 3, 2019.

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TUMORI KOD DAROVATELJA BUBREGA – ETIČKA DILEMA U TRANSPLANTACIJSKOJ MEDICINI

MARKO BANIĆ ; University of Zagreb, School of Medicine and Zagreb University Hospital Centre, Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Zagreb, Croatia
ALAN HORVAT ; University of Zagreb, School of Medicine and Zagreb University Hospital Centre, Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Zagreb, Croatia
LEA KATALINIĆ ; Zagreb University Hospital Centre, Department of Urology, Zagreb, Croatia
VESNA FURIĆ-ČUNKO ; Zagreb University Hospital Centre, Department of Urology, Zagreb, Croatia
IVANA JURIĆ ; Zagreb University Hospital Centre, Department of Urology, Zagreb, Croatia
TVRTKO HUDOLIN ; University of Zagreb, School of Medicine and Zagreb University Hospital Centre, Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Zagreb, Croatia
ŽELJKO KAŠTELAN ; University of Zagreb, School of Medicine and Zagreb University Hospital Centre, Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Zagreb, Croatia
NIKOLINA BAŠIĆ-JUKIĆ orcid id orcid.org/0000-0002-0221-2758 ; University of Zagreb, School of Medicine and Zagreb University Hospital Centre, Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation and Zagreb University Hospital Centre, Department of Urology, Zagreb, Croatia

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Abstract

Primatelji solidnih organa imaju 3-4 puta veću pojavnost zloćudnih tumora, no osim tumora vlastitog tkiva, primatelji organa mogu razviti i zloćudnu bolest povezanu s darovanim organom. Prema istraživanjima izvan Republike Hrvatske, udio bolesnika koji razviju zloćudni tumor prenesen s darovatelja iznosi 0,01-0,05 %, što bi u hrvatskim uvjetima značilo 0,02-0,1 bolesnika s prenesenim zloćudnim tumorom godišnje. Rizičnima za prijenos tumora smatraju se darovatelji stariji od 45 godina te oni s preboljelim zloćudnim tumorom u anamnezi. Jasne smjernice još nisu razvijene pa svakom bolesniku treba pristupiti individualno i procijeniti rizike i boljitke postupaka. Četiri slučaja transplantacije bubrega s moždano-mrtvog darovatelja za koje se autopsijom doznalo za malignu bolest zabilježena su i na KBC-u Zagreb.

Keywords

transplantacija bubrega; darovatelj bubrega; tumor; primatelj bubrega; etika

Hrčak ID:

230108

URI

https://hrcak.srce.hr/230108

Publication date:

5.12.2019.

Article data in other languages: english

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