Original scientific paper
COMPARISON OF PREOPERATIVE AND POSTOPERATIVE FINDINGS OF HISTOLOGIC TUMOR TYPES AND HISTOLOGIC GRADE IN PATIENTS WITH ENDOMETRIAL CARCINOMA
ALJOŠA MANDIĆ
orcid.org/0000-0002-6719-8694
; University of Novi Sad, Faculty of Medicine and Oncology Institute of Vojvodina, Novi Sad, Vojvodina, Serbia
TAMARA ĐURIČIĆ
; Oncology Institute of Vojvodina, Novi Sad, Vojvodina, Serbia
BOJANA GUTIĆ
; University of Novi Sad, Faculty of Medicine and Oncology Institute of Vojvodina, Novi Sad, Vojvodina, Serbia
IVOR KOLARSKI
; University of Novi Sad, Faculty of Medicine, Novi Sad, Vojvodina, Serbia
TATJANA KAPICL IVKOVIĆ
; University of Novi Sad, Faculty of Medicine and Oncology Institute of Vojvodina, Novi Sad, Vojvodina, Serbia
ZORAN NIKIN
; University of Novi Sad, Faculty of Medicine and Oncology Institute of Vojvodina, Novi Sad, Vojvodina, Serbia
Abstract
Purpose: Our aim was to determine the degree of agreement between preoperative and postoperative histologic type/ subtype and degree of tumor differentiation, and to determine the degree of upgrading and downgrading in relation to preoperative and postoperative histopathologic findings. Methods: We analyzed data on 393 patients. Data included age, preoperative and postoperative histologic type/subtype and histologic grade of tumor. Data on 317 patients were included in statistical processing. Results: Statistical analysis showed moderate agreement between preoperative and postoperative histologic type/subtype of endometrial carcinoma and low degree of agreement between preoperative and postoperative histologic grade of tumor. The lowest agreement in histologic grade was recorded in patients with histologic grade 1 (55.04%), while most accurate agreement was found in patients with grade 3 (73.33%). There was a low degree of agreement between preoperative and postoperative histologic grade in patients with endometrioid adenocarcinoma in both cases. The lowest accuracy in the agreement of histologic grade was in G1, while grades 2 and 3 were similar in the degree of agreement. Conclusions: There is moderate agreement of preoperative and postoperative histologic type/ subtype and low agreement of preoperative and postoperative histologic grade of tumor. The lowest degree of agreement was recorded for preoperatively G1 tumors and highest for preoperatively G3 tumors, which is important because of the clinical significance of tumor histologic grade 3.
Keywords
endometrial carcinoma; histologic type; histologic grade
Hrčak ID:
230808
URI
Publication date:
5.12.2019.
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