Conference paper

PHARMACEUTICAL FORMS OF IRON IN FOOD SUPPLEMENTS

Lejla Dedić orcid.org/0000-0001-9701-5564 ; Public Institution City Pharmacy Srbrenik, Bosnia and Herzegovina
Ivan Vukoja ; Požega County General Hospital, Croatia
Midhat Jašić ; Faculty of Technology, University of Tuzla, University 8, 75000 Tuzla, Bosnia and Herzegovina
Daniela Čačić-Kenjerić ; Faculty of Food Technology Osijek J. J. Strossmayer University of Osijek, Franje Kuhača 20, 31000 Osi-jek, Croatia
Ines Banjari ; Faculty of Food Technology Osijek J. J. Strossmayer University of Osijek, Franje Kuhača 20, 31000 Osi-jek, Croatia

Abstract

Until recently, the most commonly used iron preparation was iron sulfate, and today it is increasingly used preparations where iron is bound into complexes with organic compounds. This improves the quality and bioavailability of iron pharmaceutical forms in medicines and dietary supplements. These preparations used as medicines or dietary supplements for anemia.
The aim of the paper was to analyze the available scientific information, as well as the data from the market supply of iron supplements, its chemical composition, pharmaceutical forms and bioavailability.
The most commonly used formulations in iron supplementation are: iron (II) fumarate, iron (III) hydroxide in carbohydrate polymer - polymaltose, complex of iron (III) hydroxide with sucrose, suspension of iron (III) protein succinylate, iron (II) gluconate and forms of iron originating from hemoglobin. In these preparations iron is in two valence and trivalent form.
For better utilization, iron formulations often contain vitamins such as ascorbic acid, cyanocobalamin, folic acid and others. Most often, supplements are in the form of capsules and film-coated tablets, and there are preparations in liquid form.
The form of administration of dietary supplements should be adapted to the principles of individual nutrition and integrative medicine, so that the doses of the preparation and diet should be harmonized. The dose of the dietary supplement is determined on the basis of an assessment of health and nutritional status as well as other factors.
Today, various pharmaceutical forms of iron are used in dietary supplements, both in chemical composition and pharmaceutical dosage forms, which enables better results of their practical application.

Keywords

iron; dietary supplements; anemia

Hrčak ID:

233007

URI

https://hrcak.srce.hr/233007

Publication date:

31.12.2019.

Article data in other languages: croatian

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