Original scientific paper

https://doi.org/10.15836/ccar2020.255

Prosthetic Valve Malfunction; Etiologies, Treatment Strategies and Treatment Outcomes: A Descriptive-analytic Study

Hasan Haghaninejad ; Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Farkhondeh Khaleghi ; Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Aryan Naghedi orcid.org/0000-0002-0692-2183 ; Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract

Background: Valvular heart diseases are common worldwide and are associated with a high rate of mortality and morbidity. Surgical valve replacement is the most important treatment for valvular diseases. One of the most important complications of this treatment is prosthetic valve malfunction which requires rapid diagnosis and treatment. In this study, we examined the etiologies, treatment strategies, and treatment outcomes in a series of patients with prosthetic valve malfunction.
Patients and Methods: In this cross-sectional, analytic-descriptive study, 63 cases in 52 patients with prosthetic valve malfunction were included. Their coagulation status, demographic, and clinical information was collected in a questionnaire. Patients treatment and their outcomes or rehospitalization rate was recorded as well. Data were analyzed using SPSS 20 software.
Results: In our study population, average age was 49.98±14.31, and 53.9% of patients were women. Among 63 cases, 57 of them had mechanical valve malfunction and 6 of them had biological valve malfunction. All cases of mechanical valve malfunction were caused by thrombosis. Surgery was the most common treatment strategy and was associated with excellent outcomes compared with other strategies (p=0.002). In this study, we observed acceptable outcomes for thrombolytic therapy.
Conclusion: Thrombosis was the most frequent cause of prosthetic valve malfunction in this study, which seems to be due to inadequate anticoagulant therapy. It can be concluded that educating and following patients for their accurate coagulation status is necessary for decreasing prosthetic valve malfunction. We also found surgical treatment to be significantly better than other treatments.

Keywords

valve prosthesis; surgical valve; thrombosis; thrombolytic therapy; heart valve diseases

Hrčak ID:

242967

URI

https://hrcak.srce.hr/242967

Publication date:

28.8.2020.

Article data in other languages: croatian

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