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https://doi.org/10.37797/ig.40.2.3

Critically ill patients with COVID-19 treated in the Intensive Care Unit atthe University Hospital for Infectious Diseases „Dr. Fran Mihaljević“ in Zagreb

Anita Atelj ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Vladimir Krajinović ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Marija Santini ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia; School of Medicine, University of Zagreb, Croatia
Neven Papić ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia; School of Medicine, University of Zagreb, Croatia
Martina Vargović ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Viktor Kotarski ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Branimir Gjurašin ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Juraj Krznarić ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia
Marko Kutleša ; University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Zagreb, Croatia; School of Medicine, University of Zagreb, Croatia


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Abstract

Objective: To describe the characteristics, clinical course, treatment, outcomes and complications in critically ill patients with COVID-19 treated in the intensive care unit (ICU) at the University Hospital for Infectious Diseases „Dr. Fran Mihaljević“ (UHID) in Zagreb.
Materials and methods: A retrospective observational study of 38 adult patients with COVID-19 treated in the ICU at UHID between March 11 and June 6, 2020.
Results: Among the 167 patients with COVID-19 treated at the UHID, 38 (22,8%) were admitted to the ICU. The mean age of these patients was 69.5 (33-85) years, 70 (43-85) years in deceased patients and 66 (33-80) in survivors. The majority of patients were male (26 patients- 68%). The mMost common comorbidities were arterial hypertension (20- 53%), diabetes mellitus (9- 24%) and ischaemic heart disease (8- 21%). All patients were admitted for hypoxaemic respiratory failure. In addition to acute respiratory failure with the need for mechanical ventilation (30- 79%), shock (25- 66%) and acute renal insufficiency (21- 55%) were common. Continuous renal replacement therapy was used in 13 (34%) patients. The median duration of ICU stay was 18 (3-68) days and of mechanical ventilation 19 (5-43) days. Overall mortality was 50%, 63% in patients who received mechanical ventilation and it was the highest in patients over 65 years of age.
Conclusions: Patients with COVID-19, treated in the ICU, often require prolonged mechanical ventilation, have numerous complications of critical illness and ICU treatment, and high mortality rates. Mortality rate is highest in men over 65 years with comorbiditeies – arterial hypertension, diabetes mellitus and ischaemic heart disease.

Keywords

COVID-19; critically ill; extensive treatment

Hrčak ID:

245996

URI

https://hrcak.srce.hr/245996

Publication date:

12.11.2020.

Article data in other languages: croatian

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