Review article

Challenges to antimicrobial susceptibility testing of plantderived polyphenolic compounds

Marina Bubonja-Šonje orcid.org/0000-0001-6565-3377 ; Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Department of Clinical Microbiology, Clinical Hospital Centre Rijeka, Rijeka, Croatia
Samira Knežević orcid.org/0000-0003-3550-2062 ; Clinic for Infectious Diseases, Clinical Hospital Centre Rijeka, Rijeka, Croatia
Maja Abram ; Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Department of Clinical Microbiology, Clinical Hospital Centre Rijeka, Rijeka, Croatia

Abstract

As multidrug resistance gains momentum, the last two decades have seen an ever-growing interest in the antimicrobial properties of plant extracts and plant-derived compounds. Most of the focus is on polyphenols – a large and diverse group of phytochemicals with strong antibacterial activity. Testing methods provide reliable results as long as they follow standard procedures. However, methods and procedures used in antimicrobial susceptibility testing (AST) are often too diverse to allow comparison of results. The lack of uniformity and comparability is much owed to the absence of guidelines. The focus of this review is to give a critical overview of different methods used in the assessment of polyphenols antimicrobial efficacy and to highlight the importance of their standardisation.

Keywords

antibiogram; AST; plant-derived compounds; polyphenols; standardisation

Hrčak ID:

248035

URI

https://hrcak.srce.hr/248035

Publication date:

23.12.2020.

Article data in other languages: croatian

Visits: 2.291 *