Original scientific paper

Synthesis of Optically Active 2-Aminooctadecanes

M. Munk-Weinert ; Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yu.goslavia
M. Proštenik ; Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yu.goslavia

Abstract

2-Octadecanone has been converted to DL-2-benzylaminooctadecane by reductive amination with benzylamine. The resolution of the racemic base has been effected through its salts with benzoyl-L-alanine and benzioyl-D-alanine. Both enantiomeric bases were debenzylated hydrogenolytically to give (+) and (-)-2-aminooctadecane. A series of derivatives of the racemic and of the optically active base has been prepared.

Keywords

Hrčak ID:

249423

URI

https://hrcak.srce.hr/249423

Publication date:

31.7.1954.

Visits: 663 *