Acta clinica Croatica, Vol. 59. No. 4., 2020.
Case report
https://doi.org/10.20471/acc.2020.59.04.26
Morphea and Lichen Sclerosus in a Patient with Hyporthyroidism
Beata Bergler-Czop
; Department of Dermatology, Silesian Medical University in Katowice, Katowice, Poland
Ligia Brzezińska-Wcisło
; Department of Dermatology, Silesian Medical University in Katowice, Katowice, Poland
Abstract
Thyroid gland is one of the key organs regulating the metabolism of carbohydrates,
proteins and fats. Its primary function is connected with increase of the metabolic conversion of the
body. Skin lesions are often one of the first symptoms of hypothyroidism. In a 71-year-old patient,
skin lesions in the form of thickened areas with severe hyperkeratosis first appeared 12 years before.
Eight years before, the patient was diagnosed with hypothyroidism of unknown cause. Upon admission,
lesions were observed in the trunk area, left arm and vulva. These lesions had the appearance of
brownish spots with hyperkeratosis. Initially, they were localized on the trunk, then involving upper
limbs and neck area with time. Significant progression was present in the back area. In the anogenital
area, porcelain-white discolorations were observed. Laboratory examinations were normal. During
hospital stay, iv. ceftriaxone at a dose of 2.0 g/day for 10 days and intramuscular injection of vitamin
B6 were administered, along with 10% urea ointment for hyperkeratosis lesions as topical therapy. The
patient had lesions in the form of skin induration and discoloration, with visible, very severe hyperkeratosis,
which is not characteristic of changes of the scleroderma and lichen sclerosus type. These
lesions caused diagnostic problems due to the atypical clinical appearance.
Keywords
Hypothyroidism; Skin; Hyperkeratosis
Hrčak ID:
255234
URI
Publication date:
1.12.2020.
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