Kinesiology, Vol. 17. No. 1., 1985.
Original scientific paper
Quantitative changes in genoms of skeletal diaphragmal and heart mionuclei caused by chronic hypertension
Milan Ćabrić
; Filozofski fakultet, Studij tjelesnog dogoja u Splitu
Nigel T. James
; Department of Anatomy and Cell Biology, University of Sheffield, Sheffield, England
Abstract
The training procedure intiated in experiemntal animal a hyperplasis of mionuclei (15.2-35.9%) in the cells of skeletal muscles, diaphragm muscles and miacord of the left ventricule. Relating the measured number of nuclei in the unit of volume of muscle tissue with the biochemically determined amount of DN in one nucleus, the authors have made a quantitative estimate of the increase in concentration of DNA, caused by training effort. The authors also believe that the so called nucleotype effects, a consequence of enlargement of genoms, is the basic factor in hyperthropy of muscles and hyperphlasia of their cell elements, including the capilary network.
Keywords
steometric analysis; skeletal muscle; diaphragm muscle; heart muscle; mionucleus; DNA; animal experiments
Hrčak ID:
255860
URI
Publication date:
4.4.1985.
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