Acta clinica Croatica, Vol. 60. No. 1., 2021.
Original scientific paper
https://doi.org/10.20471/acc.2021.60.01.15
Evaluation of the Relationship of MPV, RDW and PVI Parameters with Disease Severity in Covid-19 Patients
Dilek Atik
orcid.org/0000-0002-3270-8711
; Department of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey
Hasan Burak Kaya
orcid.org/0000-0001-8851-2614
; Department of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey
Abstract
Coronavirus was first detected in three severe pneumonia cases in Wuhan, China,
in December 2019. Studies on red cell distribution width (RDW-CV) and mean platelet volume
(MPV) laboratory parameters, which can be examined in complete blood count in COVID-19 patients,
are still very limited. However, to the best of our knowledge, there are no studies examining the
relationship between platelet volume index (PVI) and disease severity in COVID-19 patients, which
was evaluated in this study. The aim of this study was to evaluate the relationship of disease severity in
COVID-19 patients with their MPV, RDW, and PVI parameters. The study included 92 COVID-19
patients as a study group and 84 healthy individuals as control group. All laboratory data and radiological
images were scanned retrospectively from patient files and hospital information system. Evaluation
of the RDW-CV and MPV blood parameters, and PVI measured in COVID-19 patients yielded
statistically significant differences according to the disease severity. We suggest that RDW-CV and
PVI, evaluated within the scope of the study, may be the parameters that should be considered in the
early diagnosis of the disease, from the initial stages of COVID-19. In addition, we think that the
RDW-CV and MPV laboratory parameters, as well as PVI, which all are simple, inexpensive and
widely used hematologic tests, can be used as important biomarkers in determining COVID-19 severity
and mortality.
Keywords
COVID-19; Disease severity; Mean platelet volume; Red cell distribution width; Platelet volume index
Hrčak ID:
259900
URI
Publication date:
1.3.2021.
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