Original scientific paper
https://doi.org/10.15255/KUI.2021.062
Hemi-synthesis of Thione and Thiol Derivatives from Artemisia judaica L. Essential Oil, and Antimicrobial Tests
Asma Drioueche
; Chemical Engineering Laboratory (LGC), University of Blida1, Faculty of Technology, B. P. 270, Soumaa road, 09000 Blida, Algeria
Hocine Boutoumi
; Chemical Engineering Laboratory (LGC), University of Blida1, Faculty of Technology, B. P. 270, Soumaa road, 09000 Blida, Algeria
Nabahat Benmansour
; University of Blida1, Faculty of Natural and Life Sciences, Department of Biology, B. P. 270, Soumaa Road, 09000 Blida, Algeria
Hichem Lettreuch
; Materials and Environment Laboratory, University Yahia Fares of Médéa, 26 000 Médéa, Algeria
Abstract
The applications of organosulfur compounds, especially thioketones are varied which concerns both synthetic and biological chemistry. In this context, from the essential oil of Artemisia judaica L., extracted by hydrodistillation, and consisting mainly of piperitone (91.77 %), thione, and thiol derivatives were hemi-synthesized via a thionylation reaction byphosphorus pentasulphide (P2S5). The possible thione-thiol tautomerism in solution followed spectrophotometrically revealed the predominance of thiol form in solution. The antimicrobial activity of essential oils showed that the thionylation of essential oil caused a considerable increase in antimicrobial activity in particular against Escherichia coli.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords
Artemisia judaica L.; essential oil; thionylation; tautomerism; antimicrobial activity
Hrčak ID:
277636
URI
Publication date:
15.5.2022.
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